Post-Doctoral Fellow in ASO brain delivery (H/F)Job Opportunity: Post-Doctoral Fellow in Neurological Disease Treatment

Are you passionate about advancing treatments for brain neurological diseases? We are seeking a highly motivated post-doctoral fellow to join our team and tackle the challenge of delivering antisense oligonucleotides (ASOs) across the blood-brain barrier (BBB). This project aims to evaluate and validate innovative delivery approaches that ensure high brain specificity for ASOs.

Why Join Us?

• Innovative Research: Delivering ASOs across the BBB remains a major bottleneck in treating brain neurological diseases. While several approaches have been identified, they require further optimization for clinical application.
• Impactful Work: Contribute to groundbreaking research that has the potential to revolutionize the treatment of neurological diseases.
• Collaborative Environment: Work closely with a multidisciplinary team, including chemists, pharmacologists, toxicologists, and other scientists, to ensure the alignment and integration of research findings.

Responsibilities:

• Collaborating with the chemistry department to deliver optimal constructs.
• Conducting in vitro evaluations on neurons (training provided if needed).
• Coordinating in vivo evaluations with DMPK, pharmacologists, and toxicologists.
• Partnering with internal and external collaborators.
• Staying updated with scientific advancements (literature review, new techniques).
• Supporting data collection and sharing with R&D partners.
• Organizing project review meetings, presenting data, and writing reports.
• Communicating results through peer-reviewed journals and conference presentations.
• Contributing to lab activities, mentoring students, and engaging in science outreach.

Description du profil :

Profile:

• PhD in in vitro Neurosciences or equivalent.
• Previous post-doc experience in in vitro neuroscience is a plus.
• Experience in in vitro culture and cellular microscopy.
• Experience in neuronal in vitro culture is a plus.
• Willingness to perform in vitro/in vivo experiments.
• Basic knowledge in the ASO field.
• Knowledge in chemistry and DMPK/Distribution is a plus.
• Fluent in English and French.
• Ability to mentor interns or technicians.
• Team spirit, proactive, and result-oriented.
• Strong communication skills and experience in writing and publishing in international peer-reviewed journals.