Reporting to the Head of Cell Engineering and Analysis Platform, you will be responsible for target validation, cell modeling and molecular biology-based technology development. This role will involve close cross-functional collaboration with project teams to design and perform assays that are critical to support oncology projects. You will participate in innovative programs in the Research Pharmacology Unit, within a stimulating environment to explore cutting-edge technologies with a high potential for scientific impact.

Principal Accountabilities:

• Discover and validate innovative targets
• Design and conduct scientific experiments and studies, make detailed scientific observations, analyze data, interpret and present results
• Develop new format/concepts for disease relevant cellular models (2D/3D models, microfluidics, organoids, …)
• Elucidate key mechanisms of action of drugs (small molecules or biologics) in target cells
• Evaluate, implement and develop core-expertise in innovative methodologies and techniques
• Collaborate in the design and analysis of genomic editing strategies, within the framework of advanced biotechnology research projects
• Contribute to the progress of oncology projects and strategic decision-making by joining the Core Team of experts
• Manage outsourcing requests
• Rigorously document protocols and results within the framework of quality assurance.
• Follow and optimize business process guiding operational workflow (tools and cell declaration and ministerial requests)
• Lead and develop a small team by providing scientific guidance, career development support, and foster a collaborative and high-performing culture.
• Ensure clear communication of objectives, empower team members, monitor performance, and act as a role model with a focus on scientific excellence and integrity

Description du profil :

Desired Profile:

Academic Background

Ph.D and a post-doc in basic research, cancer biology, cell biology, molecular biology, biotechnology, or a related field

Expertise

• Strong expertise in cellular cancer biology and cell culture 2D/3D/organoids/iPSCs
• Extensive knowledge in cell engineering and gene editing (molecular biology, CRISPR-Cas editing strategies)
• Practical knowledge in cellular assays (flow cytometry, imaging, biochemistry)
• Experience in conducting biology programs for drug discovery projects
• Capability to manage, inspire and motivate team members, fostering a positive, empowering and collaborative work environment that encourages high performance and innovation toward a common objective
• Ability to make informed and timely decisions, especially in challenging situations, ensuring the team stays focused and aligned with strategic goals

Soft Skills

• Strong collaborative skills and ability to work effectively in multidisciplinary teams
• Proactive, problem solving and decision-making skills.
• Perfect communication and presentation skills, both written and oral (French/English)

Experience

5+ years of experience in cancer biology, drug discovery (academic/biotech/pharma)