Post-Doctoral Fellow in Oncology

Are you a dynamic and innovative researcher passionate about advancing brain cancer treatment? We are seeking a post-doctoral fellow to join our oncology drug discovery team, focusing on Glioblastoma (GBM). This is a unique opportunity to play a crucial role in exploring DNA Damage Response (DDR) pathways in GBM, understanding its role in tumor progression/resistance and ultimately contributing to the development of novel therapeutic strategies.  

Why Join Us?

• Impactful Research: Glioblastoma (GBM) is the most common, aggressive, and heterogeneous malignant brain tumor with a very high unmet need. DDR pathways are often altered and dysregulated in GBM tumors, contributing to resistance to conventional therapies. This highlights a significant medical need and an area ripe for innovative research. 
• Innovative Environment: Lead efforts to dissect DNA damage and repair pathways in GBM, implementing new imaging technologies to measure DNA breaks and explore DDR in 2D & 3D GBM cellular models. Make a significant impact in oncology by addressing critical unmet medical needs.  
• Collaborative Team: Work alongside multidisciplinary teams to ensure alignment and integration of research efforts with broader organizational goals. 

Responsibilities :

• Design and implement relevant studies to explore DDR in GBM cellular models.
• Develop and implement new imaging technologies to measure DNA damage and associated DDR pathways, including biomarkers.
• Analyze data and propose the next steps in research.
• Collaborate with multidisciplinary teams (e.g., In Vitro Pharmacology, US Research, Integrative Molecular Pharmacology, Translational Medicine).
• Follow literature in the field of DDR and GBM.
• Support associated projects with new findings. Present research findings at internal meetings.
• Prepare and publish scientific manuscripts.

Description du profil :

Profile :

• PhD in Oncology.
• Experience in cancer cell biology, biochemistry, and pharmacology.
• Proven research record, including conceptual work that resulted in a first-author publication (or in the process of publishing).
• Expertise in imaging technologies, 2D and 3D cultures, and silencing technologies.
• Experience in DDR pathways.
• Experience in brain tumors is a plus.
• Ability to collaborate in an integrated, multi-disciplinary, and international team environment with a willingness to share knowledge. 
• Autonomous, proactive, rigorous, innovative, and committed team player.
• Mastery of oral and written English; French is a plus.