Company Description

As a global key player in yeasts and fermentation, Lesaffre designs, manufactures and markets innovative solutions for Baking, Food taste & pleasure, Health care and Biotechnology.

Family group born in northern France in 1853, now a multi-national and a multicultural company, Lesaffre is committed to working with confidence to better nourish and protect the planet.

In close collaboration with its clients and partners, Lesaffre employs 11 000 people in more than 50 countries.

Lesaffre achieves a turnover of 3 billion euros.

Job Description

As a scientist you will integrate Nutrition Microbiota and Heath Center of Excellence and report to the head of skin health research. Based on your expertise and collaboration opportunities within the R&D Team, you will implement imaging techniques to explore plausible mechanisms of actions and support substantiation of our products coupling cellular models with automated imaging to study microorganism-based solutions and their derivates.

Additionally, your mission will also consist of implementing high content imaging-based screening approaches to identify new bioactive and feed the innovation pipe of cosmetics, human and animal health Business units of Lesaffre.

As a skilled automated imaging engineer, you will oversee the set-up of a newly acquired High-Content Imaging (HCI) device, supervise its maintenance, develop and validate cellular assays in collaboration with other team members and project managers. While working closely with the other scientists in the R&D Team, you will promote this new technology and support new users with ad hoc assistance in assay development, training and troubleshooting sessions.  

Key responsibilities

• Supervision of the installation, use and maintenance of HCI device
• Define the safe and best practices in the facility with up-to-date Standard Operating Procedures (SOP) and Methods & Protocols (MP)
• Be involved in the laboratory daily life in compliance with existing HSE rules
• Develop, optimize and validate cellular assay protocols in epifluorescence, confocal and phase contrast settings, alone and in close collaboration with biologists
• Carry out experiments independently (2D and 3D cell culture, molecular biology and imaging assays)
• Ensure data acquisition, management and quality control with Biodata team support
• Collaborate with Biodata team to test software and develop relevant analysis strategies
• Support project teams and work package execution on-time
• Train and supervise the user community, promote and develop the facility
• Communicate and share results or issues with team members and stakeholders
• Propose and develop new screening assays with high-quality track-record (electronic lab-book, internal reports etc…)

• PhD in cell biology, biotechnology or related field with strong background in cell-based assays
• 3-5 years track-record experience in the configuration and management of an automated microscope for high content imaging in academia or in industry
• Excellent organizational, interpersonal and communication skills
• A high sense of collaboration and at ease with training people
• Structured, rigorous and precise approach, together with scientific curiosity
• Good Problem-solving skills and do-it yourself mindset are required
• Experience in histology and programming are a plus
• Fluency in English (spoken and written) is desired, other languages are a plus

Additional Information

What can Lesaffre offer you:

• Join a family business rich in a long history with human-oriented values with a mission: To Nourish and Protect our Planet, 
• Evolve in an enriching work environment and a multicultural context 

At Lesaffre, diversity is a strength that enriches our culture and our teams. We are committed to offering you a work environment where you can thrive, regardless of your background, gender, age or abilities. We encourage all applications, as we believe that diverse perspectives strengthen our ability to innovate and meet the challenges of tomorrow.