Tumor avatar technology for predicting clinical trial outcomes.
🔮 Less than 5% of new cancer drugs successfully make it through clinical trials. Clearly, new methods are needed to transform oncology research and improve patient care. Orakl Oncology is a techbio startup accelerating drug discovery and development through innovative tumor avatars. The company was established in 2023 as a spin-out from Gustave-Roussy, a leading European cancer research institute based on 10 years of research by Orakl’s CEO, Dr. Fanny Jaulin, and her laboratory.
🧪 Orakl Oncology is pioneering the use of its patient tumor avatar technology to anticipate clinical trial outcomes. We create an avatar for each patient’s tumor, combining clinical and molecular data alongside proprietary organoids, at scale, and predict patient response in the clinic. Powered by lab automation and machine learning, we discover and validate new targets, drugs, and predictive biomarkers. The VC-backed company is growing fast, and we are now seeking the best talents to come and join our exciting and ambitious team in the fight against cancer!
At Orakl Oncology, we are accelerating the development of oncology treatments. Today, fewer than 5% of new cancer drugs succeed in clinical trials. Clearly, new methods are needed. We combine cutting-edge biology and AI to build the next generation of insight platforms with the world’s largest cohort of patient tumor avatars. These avatars fuel our AI-powered predictive engine, helping to anticipate clinical trial outcomes, validate therapies, and uncover new drug candidates.
Our mission is simple yet ambitious: to bring more effective treatments to patients who need them - and to make drug development smarter, faster, and more personalized. We collaborate with top hospitals, research institutes, and pharmaceutical companies worldwide. Backed by leading investors, we are a fast-growing, mission-driven startup at the intersection of science and technology.
We are looking for a highly skilled technical profile who enjoys building new computational methods and turning them into reliable production tools. You will design, implement, and maintain computational biology methods based on multi-omics data. You will ensure that these methods are deployable on internal and external projects and robust at scale. You will work collaboratively with an interdisciplinary team of computational biologists, AI/ML experts, cell biologists, and oncologists to drive drug discovery in cancer.
This role is ideal for someone with an engineering background and a strong interest in biology, but any candidate who wants to build methods that scientists will use every day in production to advance cancer science is a strong fit.
In close collaboration with scientists, design and implement novel computational biology methods
Benchmark, validate, and compare alternative approaches; propose and test new algorithms or tools to improve performance, robustness, and scalability.
Translate research prototypes into production-ready pipelines with clear versioning and documentation. This will involve implementing and maintaining CI/CD workflows (testing, packaging, deployment, monitoring).
Collaborate with data engineering teams to run pipelines efficiently in our production environment (e.g. containers, workflow managers, cloud infrastructure).
Work closely with scientists and project teams to align on standards, architecture, and data models.
Collaborate with the experimental and data generation teams to understand data characteristics and operational constraints.
Document methods and pipelines so that non-developers can reliably use them (clear user guides, examples, release notes).
PhD and/or MSc / Engineering degree in Computer Science, Bioinformatics, Applied Mathematics, or related field.
Strong interest in biology, oncology, and translational research.
Experience with data processing for omics (RNA-seq, WES/WGS, etc.). Familiarity with common concepts, terminologies and software currently used in the field
Strong programming skills in Python, with experience developing complex libraries or pipelines.
Deep understanding of best software engineering practices.
Comfortable working in a fast-paced, technical and collaborative team.
Fluency in English is required.
Familiarity with AWS cloud infrastructure.
Demonstrated experience in curation, integration, and management of large-scale datasets.
HR Call (15 minutes call) – An initial discussion to better understand your background, experiences, and motivations.
Technical Interview (45 minutes call) – A deep dive into your technical skills and expertise relevant to the role.
Technical Case (30 minutes presentation + discussion) - A case study or problem-solving exercise to assess your strategic thinking and analytical abilities. If possible this can be done in person.
Engineering Case (45-minutes presentation + discussion) - You will be presenting a piece of work you have previously worked on and which you are proud of. This will be in front of the relevant members of the Orakl Oncology team. If possible this can be done in person.
Founders Interview: As final step of our recruitment process, you will meet the founders of Orakl Oncology in person at our office. This meeting is an opportunity for the founders to assess cultural fit and ensure alignment with our company values.
En bref
Année de création
2023
Nombre d'employés
39
Genre
48%
52%