Tumor avatar technology for predicting clinical trial outcomes.
🔮 Less than 5% of new cancer drugs successfully make it through clinical trials. Clearly, new methods are needed to transform oncology research and improve patient care. Orakl Oncology is a techbio startup accelerating drug discovery and development through innovative tumor avatars. The company was established in 2023 as a spin-out from Gustave-Roussy, a leading European cancer research institute based on 10 years of research by Orakl’s CEO, Dr. Fanny Jaulin, and her laboratory.
🧪 Orakl Oncology is pioneering the use of its patient tumor avatar technology to anticipate clinical trial outcomes. We create an avatar for each patient’s tumor, combining clinical and molecular data alongside proprietary organoids, at scale, and predict patient response in the clinic. Powered by lab automation and machine learning, we discover and validate new targets, drugs, and predictive biomarkers. The VC-backed company is growing fast, and we are now seeking the best talents to come and join our exciting and ambitious team in the fight against cancer!
Orakl Oncology develops large cohorts of patient-derived organoids (PDO), from which we generate large volumes of data and train proprietary AI algorithms to help pharma teams develop new treatments for patients. In practice: we culture ~100 PDOs in parallel at any given time in the lab, screen dozens of drugs weekly and own a growing biobank with and an expanding client portfolio.
As Biobank Operations Engineer, you will ensure the operational execution and the integrity of the traceability chain (both physical and informational) for biobank samples, from collection/reception through to release for projects, in compliance with quality and contractual requirements.
You will have a direct and strong impact on the scientific and operational quality of the data we produce. We expect you to work with a high level of autonomy and you will report directly to the Biobank Lead.
Receive, register, and qualify biological samples (fresh or frozen) in accordance with established procedures
Ensure complete traceability of samples throughout their lifecycle (receipt, processing, storage, shipment)
Aid in the planning and prioritising of biobanking activities
Participate in the structuring, characterisation, expansion and operation of the ORAKL ONCOLOGY avatar bank;
Analyse and interpret experimental results;
Maintain and improve inventory management systems (LIMS/internal database) — you will be the team's primary reference for these
Independently carry out laboratory procedures (thawing, culture, sample preparation, and quality control operation) with a high level of technical precision
Flag, document, and escalate any anomaly or deviation to the Biobank Manager
Apply and enforce quality procedures (SOPs, GLP) within the team
Draft, update, and improve SOPs related to biobanking activities
Manage non-conformities: identification, documentation, corrective action proposal and follow-up
Ensure compliance with applicable hygiene and safety requirements
Contribute to regular reporting to the Biobank Manager (activity, incidents, needs)
Support the skills development of technicians and interns within the team
Master's degree (or equivalent) in life sciences (biology, biochemistry, biotechnology or related field)
Significant experience (3+ years) in a laboratory environment or biobank setting
Proven experience in cell culture techniques (including organotypic models) and cryopreservation
Knowledge of laboratory quality systems (SOP writing, document management, traceability)
Self-driven, rigorous and able to prioritise in a multi-project environment;
Excellent communication
Fluent in English
Experience in a startup or fast-growing environment
Interest in technology watch and life sciences innovation
Interest in process improvement and operational tooling
HR Call (25 minutes call) – An initial discussion to better understand your background, experiences, and motivations.
Technical Interview (60 minutes call) – A deep dive into your technical skills and expertise relevant to the role.
Technical Case (30 minutes presentation + discussion) - A case study or problem-solving exercise to assess your strategic thinking and analytical abilities. If possible this can be done in person.
Founder Interview: As final step of our recruitment process, you will meet the founders of Orakl Oncology in person at our office. This meeting is an opportunity for the founders to assess cultural fit and ensure alignment with our company values.
En bref
Année de création
2023
Nombre d'employés
39
Genre
48%
52%