In this position, you will :

• Perform 3D PDO culture experiments following established protocols and conduct initial analyses of the data

• Participate in the development and optimisation of new cell culture protocols

• Participate in the development and optimisation of CRISPR screening assays

• Maintain the Orakl Oncology biobank: you will participate expanding and conserving the biobank and in quality control experiments

• Implement state-of-the-art processes and good engineering practices (LIMS/eLN, sample traceability etc.).

• Conduct assay development and optimisation with senior lab members

• Participate in the lab maintenance and keep the experimental infrastructure in shape

The employee will be report to a Principal Scientist in the Orakl Oncology research team. They will be trained to be able to conduct experiments on our patient-derived models so that they will become autonomous on all our activities.

Minimum qualifications:

• MSc in molecular/cellular biology, genetics, biotechnology, bioengineering or similar.

• Extensive lab experience.

• Hands-on experience in mammalian cell culture, 3D cell culture and preferably organoid culture.

• Basic knowledge in molecular biology (RT PCR, qPCR, Western Blot, DNA and RNA isolation etc.).

• Exceptional attention to detail and organisational rigour.

• Flexibility, resourcefulness and a history of overcoming operational challenges.

• A genuine enthusiasm and passion for teamwork and learning.

• Fluency in English is required

Preferred qualifications:

• Basic knowledge of microscopy and image analysis

• Basic knowledge of programming e.g. Python

• Prior experience in high-throughput experiments or lab automation

• A general understanding and genuine curiosity for cancer biology

• Strong communication skills

First Interview (30-minute call) – An initial discussion to better understand your background, experiences, and motivations.

Second Interview (Technical Capabilities) – A deep dive into your technical skills and expertise relevant to the role.

Third Interview (Use-case) – A case study or problem-solving exercise to assess your strategic thinking and analytical abilities.

Fourth Interview (Lab-case) – A lab-based exercise to assess your experimental abilities.

Fourth Interview (Cultural Fit) – A conversation with our team to ensure alignment with our company culture, values, and ways of working.