Intern, Fermentation for Protein Purification
DNA Script

DNA Script

Intern, Fermentation for Protein Purification

L'entreprise

DNA Script

DNA Script

  • Pharmaceutique / Biotechnologique, Santé
  • Entre 50 et 250 salariés

Le poste

Intern, Fermentation for Protein Purification

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Who are they?

DNA Script is a leading company in manufacturing de novo synthetic nucleic acids using enzymatic DNA synthesis (EDS) technology. The company aims at accelerating innovation in life science and technology through the decentralization of rapid, on demand and high-quality DNA synthesis. DNA Script’s approach leverages nature’s billions of years of evolution in synthesizing DNA to set a new standard for customizing nucleic acid synthesis thus accelerating discovery in genetics, genomics, and synthetic biology. Discovery disciplines with profound impacts upon humanity such as biopharma, translational genetics and even molecular information storage all start with synthetic DNA. The company has recently initiated the commercialization of its first EDS powered platform, the SYNTAX system.

To date, DNA Script has raised over $315M of financing, with leading investors such as Coatue Management, Fidelity Management and Research, Catalio Capital Management, Casdin Capital, LSP, Bpifrance Large Ventures, Danaher, Illumina Ventures, Agilent, Merck Ventures, Sofinnova Partners, Kurma Partners and Eurazeo.

DNA Script also partners on technology and product development with leading organizations such as DARPA, IARPA, Moderna Therapeutics, GE Research, Illumina, the Broad Institute, Harvard University, Institut Pasteur and the French Department of Defense.

DNA Script has its research and manufacturing facilities headquartered in Paris, France, and is in the process of expanding its commercial and development teams in South San Francisco.

DNA Script
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Job description

DNA Script

DNA Script is a leading company in manufacturing de novo synthetic nucleic acids using enzymatic DNA synthesis (EDS) technology. The company aims at accelerating innovation in life science and technology through the decentralization of rapid, on demand and high-quality DNA synthesis. DNA Script's approach leverages nature's billions of years of evolution in synthesizing DNA to set a new standard for customizing nucleic acid synthesis thus accelerating discovery in genetics, genomics, and synthetic biology. Discovery disciplines with profound impacts upon humanity such as biopharma, translational genetics and even molecular information storage all start with synthetic DNA. The company has recently initiated the commercialization of its first EDS powered platform, the SYNTAX system.

To date, DNA Script has raised over $315M of financing, with leading investors such as Coatue Management, Fidelity Management and Research, Catalio Capital Management, Casdin Capital, LSP, Bpifrance Large Ventures, Danaher, Illumina Ventures, Agilent, Merck Ventures, Sofinnova Partners, Kurma Partners, T Rowe Price, Baillie Gifford and Eurazeo.

DNA Script also partners on technology and product development with leading organizations such as DARPA, IARPA, Moderna Therapeutics, GE Research, Illumina, the Broad Institute, Harvard University, Institut Pasteur and the French Department of Defense.

DNA Script has its research and manufacturing facilities headquartered in Paris, France, and is in the process of expanding its commercial and development teams in South San Francisco.

Opportunity and Challenges :

We are looking to assemble a team of best-in-class, innovative and passionately eager people. We want to gather their talents and skills to achieve one goal: unlock the power of “DNA-write.” We offer the opportunity of joining a dynamic, international, and highly skilled team in a pioneering startup. Our DNA On Demand platform not only has the potential to change the way the world makes and uses synthetic DNA, but also to accelerate the rate of discovery by delivering upon the promise of same-day results.

This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impacts across biological sciences.

Votre rôle

DNA Script recherche une personne dynamique et talentueuse pour rejoindre l’équipe USP du groupe Enzyme Process, pour un stage de six mois dans le domaine de la fermentation. L’objectif du projet est l’amélioration de la production d’une protéine recombinante clé dans notre technologie de synthèse enzymatique d’ADN. Vous serez amené(e) à :

  • Conduire des expériences en bioréacteurs (volumes de 500 mL à 30 L) avec un haut niveau d’excellence, afin d’assurer la génération de données précises et fiables
  • Analyser les données de fermentation et quantifier la production de protéine
  • Implémenter des nouveaux procédés afin d’améliorer la production de protéine
  • Générer des rapports pour tracking interne

Qualifications et expérience

Essentiel

  • Formation Licence Professionnelle en biologie/biotechnologies ou Dernière année de master/école d’ingénieur en biologie/biotechnologie
  • Bonnes connaissances et compétences dans les techniques de microbiologie et de biochimie, telles que la croissance bactérienne, le SDS-PAGE, les tests colorimétriques
  • Excellentes compétences organisationnelles
  • Forte motivation avec une passion pour les sciences
  • Esprit d’équipe

Souhaitable

  • Une expérience en fermentation serait un plus

Miscellaneous

  • Le poste est situé au Kremlin-Bicêtre
  • Date de début : Janvier 2023
  • Durée du stage : Six mois

Processus de recrutement

  1. Entretien en visio avec le manager
  2. Entretien sur place avec le manager, l’équipe, le RH, les co-fondateurs
  3. Vérification des références
  4. Durée: 2-3 semaines
DNA Script
DNA Script

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